留学生心理学作业参考-Comparison Of Effects Of Two Different Hormone Th

留学生心理学论文参考-Comparison Of Effects Of Two Different Hormone Therapies On Mood In Symptomatic Postmenopausal Women

 

 

Introduction

Two papers of Çagatay and Neza were researched the connection between hormone and human behavior. Cagatay researched the influence of two different hormone therapies  on mood in symptomaic postmenopausal women(Cagataty,2012). And Neza’s study proved that sex chromosome gene can play the role in sexual differentiation of female sexual behavior（Neza, 2012）. Although both two authors researched  the hormone’ influence on the female, the research topic were different. Cagatey studied patients were divided in three groups. The first group and second group were treated with transdermal estradiol and oral norethisterone acetate and oral continuous combination of noretbisterone and estradiol bemibydrate, and the third group was a control group. 两篇论文，研究了Çagatay Neza激素和人类行为之间的联系。研究了两种不同家恰泰激素治疗对绝经后妇女symptomaic情绪的影响（cagataty，2012）。和Neza的研究表明，性染色体基因可以在女性性行为的性别分化中发挥作用（Neza，2012）。虽然两位作者研究了激素对女性的影响，研究的主题是不同的。cagatey研究的患者分为三组。第一组和第二组经皮雌二醇和口服醋酸炔诺酮和雌二醇和noretbisterone bemibydrate口服连续联合治疗，和第三组为对照组。

 

 

And then through HDRS (Hamilton Depression Rating Scale),  BAI (Beck Anxiety

Inventory) and Kupperman scale assessed menopausal, anxiety and depression of patient. Through this researched methord, Cagatey proved that “transdermal or oral estradiol in combination with norethisterone can improve scores of menopausal, depression and anxiety symptoms in women with symptomatic natural menopause.” Neza through the knokout mice model of SF-2 gene, which refered into adrenal glands and gonads’ development, found out that  sex chromosome genes can affect the sexual differentiation of femal sexual behavior. Two articles proved the connection between hormone and human behavior and two researches were scientific significate. 然后通过HDRS（汉密尔顿抑郁量表），白（贝克焦虑

库存）和Kupperman量表评估绝经，患者的焦虑和抑郁。通过本文的研究方法，cagatey证明了“透皮给药或口服炔诺酮联合雌二醇可改善更年期症状评分，在自然绝经妇女抑郁和焦虑症状。”knokout Neza通过SF-2基因的小鼠模型，这称为肾上腺和性腺的发展，发现性染色体基因的影响女性性行为的性别差异。两篇文章证明了激素与人类行为和两个研究之间的关系进行科学的意义。

 

 

Literature review:

At present,  there are a lot of scholars to research the topic. Julianne found out the hormone replacement therapy (HRT) can affect well on the depressed mood among menopausal women (Julainne and William, 1997). Macro found that low-dose, continuous combined estradiol and noretisterone acetate can paly good role on menopausal quality of life in early postmenopausal women. (Macro, 2003). Following this study, he in 2005 proved that the low estrogen dose can play a postive role on the menopausal women who have sleep disturbance ( Macro, 2005).  Greert studied the efffect of the sex chromosomes on the behavior and brain’s sexual differentiatioon and found that sex chromosome genes can contribute directly to the development of a sex difference in the brain. (Greet, 2002). Phoebe found that the sexually dimorphic gene expression between male and female brain always procedes the other gonadal differentiation. (Phoebe, 2003).

 

 

The method of two academic paper is to research the topic better. Categy adopted the comparison and contrast ways to analyze the effect of  two different hormone therapies on mood in symptomatic postmenopausal women. The first group and second group were respectively treated with transdermal estradiol and oral norethisterone acetate, and oral continuous combination of noretbisterone and estradiol bemibydrate, compared with the control group which was treated with placebo. And then through HDRS (Hamilton Depression Rating Scale),  BAI (Beck Anxiety Inventory) and Kupperman scale ways, the authour analyzed the results.  At the same time,  Neza through the knokout mice model of SF-2 gene, which refered into adrenal glands and gonads’ development, found out that  sex chromosome genes can affect the sexual differentiation of femal sexual behavior. Two articles proved the connection between hormone and human behavior and two research method were very proper.   

 

 

Two researches provided the reliable research result on the connection between homrone and human behavior, which can be regarded as indispensable factors to reinforce its reliability and validity. The findings of two article both showed that the homorne or homorne gene can affect the human mood or behavior. Çagatay found out that two hormone therapies had effect on mood in symptomatic postmenopausal women. Neza proved  that the sex chromosome gene can play the role in sexual differentiation of female sexual behavior. Their dicoveries both proved the important role of homorne on human mood of behaviror, especially for female. The lastest study showen that the humorne not only affect the growth, development and emotional expression of a normal person, but also the balance of every organ system. The most imortant factor is homorne can directly the person’s psychological activity.  According the research, hormone levels remain stable in the male after puberty, while in the body of women,  it appears regular fluctuations. This change can have different effects on human mood or behavior. Through these two authors research, they can provide good example or ways to improve female’ mental health or mood.  In the future, the research on homrone will be studied for being more persuasive and more depth.

 

 

 

Reference:

1. Phoebe Dewing, et al. (2003). Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation. Molecular Brain Research. 118:1-2, 82-90.

2. Marco Gambacciani, et al. (2005). Effects of low-dose, continuous combined hormone replacement therapy on sleep in symptomatic postmenopausal women. Maturitas, 50:2, 91-97

3. Macro Gambacciani. (2003). Effects of low-dose, continuous combined estradiol and noretisterone acetate on menopausal quality of life in early postmenopausal women. Matutitas. 44:2, 157-163.

4. Greert J. De Vries (2002). http://www.ukassignment.org/plus/search.php?kwtype=0&keyword=%E5%BF%83%E7%90%86%E5%AD%A6&searchtype=titlekeyword A Model System for Study of Sex Chromosome Effects on Sexually Dimorphic Neural and Behavioral Traits. Neuroscience, 22:20,9005-9014.

5. Julainne E. Zweifel and William H. O’Brien.(1997). A meta- analysis of the effect of hormone replacement therapy upon depressed mood. Psychoneuroendocrinology. 22:3, 189-212.

6. Neza Grgurebic, et al. （2012）.Evidence that sex chromosome genes affect sexual differentiation of female sexual behavior. Hormones and Behavior, 61:5, 719-724.

7. Cagataty Karsidag, et al.(2012). Comparison of Effects of Two Different Hormone Therapies on Mood in Symptomatic Postmenopausal Women. Archives of Neuropsychiatry 49:39-43